Irf1 molecular weight
WebDec 27, 2024 · Results: IRF1 was identified as a novel TF that suppresses KPNA2 gene expression. We observed that IRF1 expression was lower in cancerous tissues than in normal lung tissues and that its low expression was correlated with poor prognosis in … WebInterferon regulatory factor 1 (IRF1) is a tumor suppressor gene often found downregulated in breast cancers; this low expression correlates with endocrine therapy resistance (Bouker et al., 2004, 2005, 2007; Gu et al., 2002 ). Approximately, 30% of cancerous breast lesions have allelic loss of IRF1 when compared with the adjacent normal breast ...
Irf1 molecular weight
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WebApr 10, 2024 · The predicted theoretical isoelectric point of pIgR amino acid sequence is 5.92, and theoretical molecular weight is 37.48 kDa, and the first 19 amino acids are signal peptides. It is predicted that there may be an N-linked glycosylation site (N 34 LTV) in the extracellular domain (Fig. 1). Download : Download high-res image (4MB) WebMay 5, 2014 · Cellular & Molecular Immunology - K63-linked polyubiquitination of IRF1: an essential step in the IL-1 signaling cascade ... Adding weight to this was the observation that SKI-1, ...
WebWhen using primary antibodies produced in mouse to detect proteins with a molecular weight in the range of 50 kDa, we recommend using Rabbit Anti-Mouse IgG (Light Chain … WebApr 16, 2002 · Molecular Function: RNA polymerase II transcription regulatory region sequence-specific DNA binding Source:ARUK-UCL. 1 publication. ... Note: MYD88-associated IRF1 migrates into the nucleus more efficiently than non-MYD88-associated IRF1. By similarity Keywords. Cellular component. #Cytoplasm; #Nucleus ...
WebIRF1 Protein Molecular Weight & PI . The parameters have been computed for the following feature . FT CHAIN 1-325 Interferon regulatory factor 1. Molecular weight (Da) 36502.21 … WebPredicted molecular weight. 32.27 kDa . Stability and Storage. Use a manual defrost freezer and avoid repeated freeze thaw cycles.Store at 2 to 8 °C for one week .Store at -20 to -80 °C for twelve months from the date of receipt. ... IRF1. Species. Human . Shipping. In general, proteins are provided as lyophilized powder/frozen liquid. They ...
WebJul 8, 2024 · IRF1 expression is associated with the expression of IFNβ, which leads to the activation of the JAK-STAT pathway. Blocking the JAK-STAT pathway with the Janus kinase inhibitor (JAKinib)...
WebMar 29, 2024 · 1 INTRODUCTION. Glioblastoma, which is believed to be generated by progenitor or neuroglial stem cells, has the highest degree of malignancy among gliomas and the highest prevalence among brain tumors. 1, 2 Glioblastoma exhibits cell and nuclear rudimentary, microvascular proliferation, a high degree of cellularity, necrosis, and mitosis … raw wheels and tires.comWebMar 21, 2024 · IRF1 (Interferon Regulatory Factor 1) is a Protein Coding gene. Diseases associated with IRF1 include Lung Cancer and Gastric Cancer. Among its related pathways are Bacterial infections in CF airways and Overview of interferons-mediated signaling … HBB (Hemoglobin Subunit Beta) is a Protein Coding gene. Diseases associated with … Gene Ontology (GO) - Molecular Function for MET Gene. GO ID Qualified GO term … VCAM1 (Vascular Cell Adhesion Molecule 1) is a Protein Coding gene. Diseases … Complete information for IWS1 gene (Protein Coding), Interacts With SUPT6H, … PHGDH (Phosphoglycerate Dehydrogenase) is a Protein Coding gene. Diseases … CCL2 (C-C Motif Chemokine Ligand 2) is a Protein Coding gene. Diseases … IFITM1 (Interferon Induced Transmembrane Protein 1) is a Protein Coding gene. … CCL19 (C-C Motif Chemokine Ligand 19) is a Protein Coding gene. Diseases … IGFBP7 (Insulin Like Growth Factor Binding Protein 7) is a Protein Coding gene. … CDKN1B (Cyclin Dependent Kinase Inhibitor 1B) is a Protein Coding gene. Diseases … simple mindset-style for the mature womanWebKO Validated STAR208P) and visualized on the ChemiDoc MP with 10 second exposure. Arrow points to IRF1 (molecular weight 47 kDa) Western blot analysis of IRF1 knockout HeLa and wild type HeLa (WT) whole cell lysates probed with (A) Rabbit anti IRF1 antibody (VPA00801STAR208P) and (B) hFAB rhodamine anti-tubulin primary antibody and … raw wheat grass powder recipeWebSep 19, 2010 · Blast analysis revealed that the porcine IRF1 gene has 85.7, 74.3 and 72.9% nucleotide identity with the corresponding human, mouse and rat IRF1 sequences, … raw wheels fulfordWebMolecular function Cellular component: Biological process ... Interferon regulatory factor 1 is a protein that in humans is encoded by the IRF1 gene. ... Body weight: Normal Anxiety: Normal Neurological assessment: Normal Grip strength: Normal Hot plate: Normal Dysmorphology: simple mindset international limited• Harada H, Taniguchi T, Tanaka N (1999). "The role of interferon regulatory factors in the interferon system and cell growth control". Biochimie. 80 (8–9): 641–50. doi:10.1016/S0300-9084(99)80017-0. PMID 9865486. • Pitha PM, Au WC, Lowther W, Juang YT, Schafer SL, Burysek L, Hiscott J, Moore PA (1999). "Role of the interferon regulatory factors (IRFs) in virus-mediated signaling and regulation of cell growth". Biochimie. 80 (8–9): 651–8. doi:10.1016/S030… • Harada H, Taniguchi T, Tanaka N (1999). "The role of interferon regulatory factors in the interferon system and cell growth control". Biochimie. 80 (8–9): 641–50. doi:10.1016/S0300-9084(99)80017-0. PMID 9865486. • Pitha PM, Au WC, Lowther W, Juang YT, Schafer SL, Burysek L, Hiscott J, Moore PA (1999). "Role of the interferon regulatory factors (IRFs) in virus-mediated signaling and regulation of cell growth". Biochimie. 80 (8–9): 651–8. doi:10.1016/S0300-9084(99… raw wheelsWebWestern blot analysis of HeLa cells, untreated or treated with Human Interferon-γ (hIFN-γ) #8901 (100 ng/ml, 4 hr), using IRF-1 (D5E4) XP ® Rabbit mAb. Western blot analysis of … simple minds edinburgh review