Eif4a3 rbp
WebDec 3, 2024 · (A) Potential binding site between EIF4A3 and hsa_circ_0068631 according to CircInteractome. (B) Pull-down silver staining was used to demonstrate the potential RBPs binding to hsa_circ_0068631. (C) Interaction between EIF4A3 and hsa_circ_0068631 was demonstrated by an RNA pull-down assay. WebOct 29, 2024 · In conclusion, CircETFA can increase the expression of CCL5 to promote the progression of HCC by sponging hsa-mir-612 and recruiting EIF4A3, and is promising as a novel biomarker and therapeutic...
Eif4a3 rbp
Did you know?
WebJun 9, 2024 · As an important RNA-binding protein, EIF4A3 was revealed to be involved in RNA exon splicing by forming exon junction complexes [ 30 ]. Moreover, EIF4A3 has been found to play a key role in regulating the progression of various tumors, such as breast cancer, glioblastoma, ovarian cancer [ 31, 32, 33 ]. WebDec 30, 2024 · RBP binding sites on 3′ ends of a gene are the most conserved across species. Phenotypic analysis on the extent of conservation of binding sites revealed the …
WebPurpose: Eukaryotic initiation factor 4A-3 (EIF4A3) is an RNA-binding protein (RBP) that is a core component of the exon junction complex (EJC). It has been identified as an important player in... WebPurpose: Eukaryotic initiation factor 4A-3 (EIF4A3) is an RNA-binding protein (RBP) that is a core component of the exon junction complex (EJC). It has been identified as an important player in ...
WebB & C. Relative protein level of FOXO1, beclin1, eIF4A3, and LC3B in ox-LDL treated HUVECs. One-way ANOVA. Compared with 0 h, ***p < 0.001. n ≥ 6. D -F. Overexpression of hsa_circ_0030042 in HUVECs. WebDec 3, 2024 · EIF4A3 is a core component of the exon junction complex (EJC), playing significant roles in mRNA splicing, location, transport, translation, and degradation. 30, …
WebEIF4A3 (eukaryotic translation initiation factor 4A3) is an RNA helicase and core component of the exon junction complex. While this RNA-binding protein (RBP) is well …
WebDec 2, 2024 · EIF4A3 (eukaryotic translation initiation factor 4A3) is an RNA helicase and core component of the exon junction complex. While this RNA-binding protein (RBP) is well-characterized for its crucial roles in splicing, RNA trafficking and nonsense-mediated decay, its role in the regulation of metabolic signaling pathways remains elusive. platform independent meaning in marathiWebEIF4A3 is a gene involved in RNA metabolism, plays a role in mandible, laryngeal, and limb morphogenesis. Richieri-Costa-Pereira syndrome is caused by mutations in EIF4A3. The binding mode of CWC22 to eIF4AIII reveals a facet of how MIF4G domains use their versatile structural frameworks to activate or inhibit DEAD-box proteins. pride month nameWebJul 15, 2024 · Eukaryotic initiation factor 4A3 (EIF4A3, DDX48) is a member of the DEAD box family, which is one of the largest helicase families characterized by an Asp-Glu-Ala-Asp (DEAD) motif . ... “RBP mediated circularization”, RBP interacts with the intron binding sites to make the splice sites closer to induce circularization. ... pride month nashvilleWebJul 16, 2015 · #Transcriptome mapping of EIF4A3 iCLIP For mapping, we compiled a set of representative mRNA sequences from BioMart Ensembl Genes 79, where we used the longest mRNA sequence available for each gene. We mapped to these mRNAs with Bowtie2.1 alignment software, allowing 2 mismatches. platform independent and portable in javaplatforming catalystWebMar 21, 2024 · EIF4EBP3 (Eukaryotic Translation Initiation Factor 4E Binding Protein 3) is a Protein Coding gene. Diseases associated with EIF4EBP3 include Thymus Lymphoma . … platform industry 4.0WebJul 21, 2024 · Abstract Eukaryotic initiation factor 4A-3 (eIF4A3) is an Asp-Glu-Ala-Asp (DEAD) box-family adenosine triphosphate (ATP)-dependent RNA helicase. Subtypes eIF4A1 and eIF4A2 are required for translation initiation, but eIF4A3 participates in the exon junction complex (EJC) and functions in RNA metabolism including nonsense-mediated … pride month near me