WebNov 10, 1983 · Then a detailed evaluation of possible chloramphenicol residues in foods of animal origin is given, showing that these residues may be either original chloramphenicol and/or numerous, partly radical, metabolites of chloramphenicol. WebOrigin of chloramphenicol particle protein ... The specific activity of chloramphenicol particle protein is independent of the time between a pulse labeling of cellular protein and the addition of the drug, showing that the protein found on chloramphenicol particles is not normally incorporated into some cellular structure from which it is ...
Chloramphenicol - Infectious Diseases - Merck Manuals …
WebApr 10, 2024 · chloramphenicol, antibiotic drug once commonly used in the treatment of infections caused by various bacteria, including those in the genera Rickettsia and … WebChloramphenicol (83) HIS3 (86) Hygromycin (229) Kanamycin (78) LEU2 (86) Neomycin (select with G418) (147) Puromycin (95) TRP1 (95) URA3 (97) Bacterial Resistance. ... rodian biology
Intraspecies transfer of a chloramphenicol-resistance plasmid …
WebA concept is presented wherein metabolites of chloramphenicol generated by intestinal bacteria undergo further metabolic transformation in the bone marrow with in situ production of toxic intermediate. WebApr 7, 2024 · In this paper, an imine-based porous 3D covalent organic polymer (COP) was synthesized via solvothermal condensation. The structure of the 3D COP was fully characterized by Fourier transform infrared spectroscopy, scanning electron microscopy, transmission electron microscopy, and powder X-ray diffractometry, thermogravimetric … Chloramphenicol was first isolated from Streptomyces venezuelae in 1947 and in 1949 a team of scientists at Parke-Davis including Mildred Rebstock published their identification of the chemical structure and their synthesis. In 1972, Senator Ted Kennedy combined the two examples of the Tuskegee Syphilis … See more Chloramphenicol is an antibiotic useful for the treatment of a number of bacterial infections. This includes use as an eye ointment to treat conjunctivitis. By mouth or by injection into a vein, it is used to treat meningitis See more Aplastic anemia The most serious side effect of chloramphenicol treatment is aplastic anaemia. This effect is rare but sometimes fatal. The risk of AA … See more Chloramphenicol is a bacteriostatic agent, inhibiting protein synthesis. It prevents protein chain elongation by inhibiting the peptidyl transferase activity … See more Although its use in veterinary medicine is highly restricted, chloramphenicol still has some important veterinary uses. It is currently considered the most useful treatment of chlamydial disease in koalas. The pharmacokinetics of chloramphenicol have been … See more The original indication of chloramphenicol was in the treatment of typhoid, but the presence of multiple drug-resistant Salmonella Typhi has meant it is seldom used for this … See more Chloramphenicol is extremely lipid-soluble; it remains relatively unbound to protein and is a small molecule. It has a large apparent volume of distribution and penetrates effectively into all tissues of the body, including the brain. Distribution is not uniform, with … See more Names Chloramphenicol is available as a generic worldwide under many brandnames and also under various generic names in eastern Europe and Russia, including chlornitromycin, levomycetin, and chloromycetin; the … See more rodian bounty hunters